This is the basic treatment in Infertility which involves stimulation of ovulation by medication. Ovulation induction uses hormonal therapy to stimulate egg development and to induce ovulation in women who do not ovulate on their own — typically women with irregular menstrual cycles.
The goal is to produce a single, healthy egg. A typical cycle begins with a baseline ultrasound on day 2 of the menstrual cycle prior to starting oral medications. Clomiphene is the most common oral medication taken on days 2-6 or 5-9 of a menstrual cycle.
A follow up ultrasound will be performed on day 11 to check for follicular development. Once the lead follicle(s) measure at least 18-20 mm in diameter, instructions are given for either timed intercourse or to take an injection of human chorionic gonadotropin (HCG) which causes ovulation followed by intrauterine insemination.
Injectable gonadotropins (FSH/ HMG) are another commonly used medications used for ovulation induction. The cycle begins with a baseline ultrasound on day 2 of the menstrual cycle prior to starting any injectable medication. Injectable medications are started on day 2 and are continued for 6 -10 days. During that time, you may require 3-4 ultrasounds to monitor the development and pace of the follicle growth. Once the lead follicle(s) measure at least 16-18 mm in diameter, an injection of human chorionic gonadotropin (HCG) is given which causes ovulation. Intrauterine insemination (IUI) or intercourse will be performed on the following 2 days after the injection of HCG.
Some women may experience bloating, nausea, breast tenderness, period like cramping. Uncommon side effect of hyperstimulation can occur wherein that cycle is abandoned. Risk of multiple births (i.e. twins or greater) is still increased slightly by this treatment.